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货号： bs-17703R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17703R-RBITC
- 英文名称
- Anti-phospho-Moesin (Thr558)/RBITC
- 中文名称
- 罗丹明（RBITC）标记的磷酸化膜突蛋白抗体
- 别 名
- Moesin (phospho T558); p-Moesin (phospho T558);Membrane organizing extension spike protein; Membrane-organizing extension spike protein; MOES_HUMAN; Moesin; Moesin/anaplastic lymphoma kinase fusion protein; MSN; MSN/ALK fusion.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 产品类型
- 磷酸化抗体
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 68kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthesised phosphopeptide derived from human Moesin around the phosphorylation site of Thr558
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]
Function:
Probably involved in connections of major cytoskeletal structures to the plasma membrane.
Subcellular Location:
Cell membrane. Cytoplasm; cytoskeleton. Apical cell membrane. Cell projection; microvillus membrane. Phosphorylated form is enriched in microvilli-like structures at apical membrane (By similarity). Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment.
Tissue Specificity:
In all tissues and cultured cells studied.
Post-translational modifications:
Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures.
Similarity:
Contains 1 FERM domain.
Database links:Entrez Gene: 4478Human
Entrez Gene: 17698Mouse
Omim: 309845Human
SwissProt: P26038Human
SwissProt: P26041Mouse
Unigene: 87752Human
Unigene: 138876Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.