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货号： bs-10488R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10488R-RBITC
- 英文名称
- Anti-parathyroid hormone/RBITC
- 中文名称
- 罗丹明（RBITC）标记的甲状旁腺激素抗体
- 别 名
- hPTH; Parathormone; Parathyrin; Parathyroid hormone 1; Parathyroid hormone; PTH; PTH1; PTH1 receptor; PTH1R; PTHR; PTHR1; PTHY_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 4kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human parathyroid hormone
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
Subunit:
Interacts with PTH1R (via N-terminal extracellular domain).
Subcellular Location:
Secreted.
DISEASE:
Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Similarity:
Belongs to the parathyroid hormone family.
Database links:Entrez Gene: 280903 Cow
Entrez Gene: 403986 Dog
Entrez Gene: 5741 Human
Entrez Gene: 19226 Mouse
Entrez Gene: 399502 Pig
Entrez Gene: 24694 Rat
Omim: 168450 Human
SwissProt: P01268 Cow
SwissProt: P52212 Dog
SwissProt: P01270 Human
SwissProt: P01269 Pig
SwissProt: P04089 Rat
Unigene: 37045 Human
Unigene: 284168 Mouse
Unigene: 9768 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.