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货号： bs-2654R 基本售价： 780.0 元 规格： 50ul
- 规格：50ul
- 价格：780.00元
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-2654R
- 英文名称
- LTB4-R1
- 中文名称
- 白三烯B4受体1抗体
- 别 名
- Leukotriene B4 receptor 1; Leukotriene B4 receptor; BLT; BLT1; BLTR; Chemokine receptor like 1; CMKRL1; G protein coupled receptor 16; GPR16; Leukotriene B4 G Protein coupled receptor; LTB4 R 1; LTB4R 1; LTB4R; LTBR1; P2RY7; P2Y purinoceptor 7; P2Y7; Purinergic receptor P2Y G protein coupled 7; LT4R1_HUMAN; LTB4-R 1; LTB4-R1; Chemoattractant receptor-like 1; G-protein coupled receptor 16; P2Y purinoceptor 7; P2Y7.
- Specific References (2) | bs-2654R has been referenced in 2 publications.[IF=0.00] Wculek, S. Pre-metastatic neutrophils directly support highly tumourigenic breast cancer cells during lung metastasis via a leukotriene-ERK1/2 axis. Diss. UCL (University College London), 2016. FCM ; Mouse.PubMed:000[IF=4.57] Zinn, Sebastian, et al. "The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons." Journal of Biological Chemistry (2017): jbc-M116. IHC-F ; Mouse.PubMed:28242764
- 规格价格
- 50ul/780元购买 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 50ul 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 免疫学 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig,
- 产品应用
- ELISA=1:500-1000 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human LTB4-R1:101-200/352 <Cytoplasmic>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Leukotriene B4 Receptor is a member of the GPCR family (subfamily:chemoattractant). It is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response. It has been reported in blood, bone marrow, brain, heart, liver, and skeletal muscle. In addition, it has been shown to be highly expressed in leukocytes and lymphoid tissues such as spleen, thymus, and lymph node. ESTs have been isolated from B cell/lung/testis, breast, colon, eye, kidney, skin, spleen, testis, and tonsil libraries.
Function:
Receptor for extracellular ATP, UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
Subcellular Location:
Cell membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.
Post-translational modifications:
Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
Q15722
Gene ID:
1241
Database links:Entrez Gene: 1241 Human
Omim: 601531 Human
SwissProt: Q15722 Human
Unigene: 567248 Human
Unigene: 727320 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.