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货号： bs-9812R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9812R-RBITC
- 英文名称
- Anti-TCF9/RBITC
- 中文名称
- 罗丹明（RBITC）标记的转录因子9抗体
- 别 名
- Chromosome 2 open reading frame 3; DNABF; GC rich sequence DNA binding factor; GC-rich sequence DNA-binding factor; GCF; TCF 9; TCF9; Transcription factor 9; GCFC2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 89kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TCF9/GCF
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
GCF, also known as C2orf3 (chromosome 2 open reading frame 3), transcription factor 9 (TCF-9) or DNABF, is a 781 amino acid nuclear protein that belongs to the GCF family. Widely expressed, GCF binds the GC-rich sequences of ∫-Actin, EGFR and calcium-dependent protease (CANP) promoters. GCF contains multiple phosphoserine and phosphothreonine residues, and two GCF isoforms are produced due to alternative splicing events. GCF is considered a candidate for susceptibility to dyslexia (DYX3) as both genes reside in close proximity on human chromosome 2. Chromosome 2 is the second largest human chromosome and consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8% of the human genome.
Function:
Factor that represses transcription. It binds to the GC-rich sequences (5-GCGGGGC-3) present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters.
Subcellular Location:
Nuclear.
Tissue Specificity:
Widely expressed in tissues and cell lines.
Similarity:
Belongs to the GCF family.
Database links:Entrez Gene: 6936 Human
Omim: 189901 Human
SwissProt: P16383 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.