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货号： bs-11287R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11287R-RBITC
- 英文名称
- Anti-Lymphotactin/RBITC
- 中文名称
- 罗丹明（RBITC）标记的淋巴细胞趋化因子抗体
- 别 名
- Lptn; LTN; XCL1 C motif chemokine 1; SCM 1 alpha; ATAC; Chemokine C Motif Ligand 1; Cytokine SCM-1; LPTN; LTN; Lymphotactin; Lymphotaxin; SCM-1-alpha; SCM1; SCYC1; Small inducible cytokine C1; Small Inducible Cytokine Subfamily C Member 1; Small-inducible cytokine C1; XC chemokine ligand 1; Xcl1; XCL1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 10kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Lymphotactin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells (1). Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines (3,4). In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary (2). Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes (1). The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family (5). The gene which encodes lymphotactin maps to human chromosome 1q23 (1,2).
Function:
Chemotactic activity for lymphocytes but not for monocytes or neutrophils.
Subcellular Location:
Secreted.
Tissue Specificity:
Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.
Similarity:
Belongs to the intercrine gamma family.
Database links:Entrez Gene: 6375Human
Omim: 600250Human
SwissProt: P47992Human
Unigene: 546295Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.