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货号： bs-11471R-RBITC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11471R-RBITC
- 英文名称
- Anti-PTPRD/RBITC
- 中文名称
- 罗丹明（RBITC）标记的酪氨酸磷酸酶PTPδ抗体 蛋白酪氨酸磷酸酶D受体抗体
- 别 名
- protein tyrosine phosphatase receptor type D; RPTP Delta; Tyrosine phosphatase Delta; PTPRD_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 212kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PTPRD (783-830aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
RelevancePTPRD is a protein tyrosine phosphatase that falls into the receptor-type group as it characteristically comprises an extracellular region, a single transmembrane region and two tandem cytoplasmic catalytic domains. The extracellular region of this protein contains 3 Ig-like and 8 fibronectin type III-like domains. This protein is thought to be involved in promoting neurite growth and in axonal guidance.
Subunit:
Interacts with IL1RAPL1 (via extracellular region); interaction is required for IL1RAPL1-mediated synapse formation (By similarity). Interacts with PPFIA1, PPFIA2 and PPFIA3.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Post-translational modifications:
A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called ectodomain shedding is thought to be involved in receptor desensitization, signal transduction and/or membrane localization.
Similarity:
Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
Contains 8 fibronectin type-III domains.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 2 tyrosine-protein phosphatase domains.
Database links:Entrez Gene: 5789 Human
Omim: 601598 Human
SwissProt: P23468 Human
Unigene: 446083 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.