Mouse IL-13 ELISpot Development Module, 5 Plate (1 KT)
货号：
SEL413 基本售价：
询价 规格：
1 KIT
产品信息
概述| 货号 | SEL413 |
| 别名 | ALRHMGC116789; BHR1interleukin-13; IL13; IL-13; IL-13MGC116788; interleukin 13; MGC116786; NC30; P600 |
全称 | Interleukin 13 | | 反应种属 | Mouse |
| 目标/特异性 | Please see the product datasheet |
| 是否允许进口 | 否 |
| 是否危险品 | 是 |
性能| 供应商 | R&D Systems |
| 检测类型 | Quantitative Sandwich ELISA Development Module |
| Entrez Gene IDs | 3596 (Human); 16163 (Mouse); 116553 (Rat); 574325 (Primate); |
| 背景 | IL-13 (Interleukin-13) plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. IL-13 suppresses the production of proinflammatory cytokines and other cytotoxic substances by macrophages, fibroblasts, and endothelial cells. It promotes B cell activation, immunoglobulin class switching to IgE, and the upregulation of CD23/Fc epsilon RII. IL-13 signals through a receptor complex containing IL-13 R alpha 1 and IL-4 R alpha. This complex also functions as the type 2 IL-4 receptor. IL-13 R alpha 2 binds IL-13 and prevents IL-13 from signaling through the IL-13 R alpha 1/IL-4 R alpha complex. IL-13-bound IL-13 R alpha 2 can directly promote tumor cell invasiveness and the development of tissue fibrosis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
