Human IL-23 p19 ELISpot Development Module, 5 Plate (1 KT)
货号:
SEL1716 基本售价:
6484.1 元 规格:
1 KIT
产品信息
概述货号 | SEL1716 |
别名 | IL23; IL-23; IL23A; IL-23A; IL-23-A; IL-23p19; IL23P19P19; interleukin 23 p19 subunit; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; Interleukin-23 subunit p19; JKA3 induced upon T-cell activation; MGC79388; SGRF; SGRFIL-23 subunit alpha |
全称 | Interleukin 23 | 反应种属 | Human |
目标/特异性 | Please see the product datasheet |
性能供应商 | R&D Systems |
检测类型 | Quantitative Sandwich ELISA Development Module |
Entrez Gene IDs | 51561 (Human); 83430 (Mouse); |
背景 | IL-23 (Interleukin-23) is a disulfide-linked cytokine composed of a p19 subunit that is unique to IL-23 and a p40 subunit that is shared with IL-12. It is produced by activated macrophages, microglia, and monocyte-derived dendritic cells in response to pathogens. IL-23 induces the earliest recruitment of neutrophils to the site of infection and promotes the development and maintenance of Th17 cells. It also enhances the development of Th17 mediated autoimmunity and tumor progression. IL-23 signals through a receptor complex consisting of IL-12 R beta 1 and IL-23 R. This complex is expressed in mouse Th1 and Th2 cells, bone marrow dendritic cells, activated macrophages and CD4+ CD45Rb(low) memory T cells. |
运输条件 | Blue Ice |
存放说明 | -20℃ |