Quantikine Immunoassay Control Set 402 for Human Fas Ligand (1 EA)
货号：
QC89 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC89 |
| 简介 | For use with catalog number DFL00B |
| 别名 | apoptosis (APO-1) antigen ligand 1; Apoptosis antigen ligand; APT1LG1CD95L; APTL; CD178 antigen; CD178; CD95L; CD95-L; Fas antigen ligand; Fas ligand (TNF superfamily, member 6); Fas ligand; FASLCD95 ligand; FASLG; TNFSF6; TNFSF6FasL; tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 356 (Human); 14103 (Mouse); 25385 (Rat) |
| 背景 | Fas Ligand (FasL), also known as CD178, CD95L, or TNFSF6, is a transmembrane protein homotrimer that binds to Fas/CD95 and triggers apoptosis in the Fas-expressing cell. Fas Ligand also binds the soluble decoy receptor DcR3. It is expressed on activated Th1 cells, CD8+ cytotoxic T cells, and NK cells. A soluble form can be released which remains trimeric and retains the ability to bind Fas. Fas Ligand-induced apoptosis plays a central role in the development of immune tolerance and the maintance of immune privileged sites. Tumor cells can evade immune surveillance by upregulating Fas Ligand to kill tumor infiltrating lymphocytes. In gld mice, a Fas Ligand point mutation is the cause of severe lymphoproliferation and systemic autoimmunity. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - An Inhibitor of Fas Ligand-induced Apoptosis
- Epithelial Cell Markers and Intracellular Molecules
- gamma delta T Cells
- Human CD Marker Products
- ICC / IHC Images: Fas Ligand/TNFSF6
- Isolation, Culture, and Identification of Natural Killer Cells
- Mini-review: Cytolytic Granule-mediated Apoptosis
- Natural Killer T (NKT) Cells
- Regulation of Apoptosis by TNF Superfamily Members
- Surface Ectodermal Cells
- TNF Superfamily
- TNF Superfamily Ligands
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