Quantikine Immunoassay Control Set 566 for Human CRP (1 EA)
货号：
QC70 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC70 |
| 别名 | C-reactive protein; C-reactive protein, pentraxin-related; CRP; MGC88244; pentraxin 1; PTX1MGC149895 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 1401 (Human); 12944 (Mouse); 25419 (Rat) |
| 背景 | C-Reactive Protein (CRP), also known as Pentraxin 1, is a secreted pentameric protein that functions as a sensor and activator for the innate immune response. In humans, it is a major acute-phase protein; its circulating concentration is dramatically elevated at the onset of inflammation. In mice, however, serum CRP levels increase only slightly during inflammation, and the analogous acute phase role is filled by Pentraxin 2. CRP binds, opsonizes, and induces the phagocytosis of bacteria and apoptotic cells. It regulates activation of the classical complement pathway by binding several proteins in the complement cascade as well as Fc gamma RI, Fc gamma RIIA, and Fc gamma RIIB on macrophages and dendritic cells. It also promotes dendritic cell maturation and humoral immunity. In cardiovascular disease, CRP binds to oxidized LDL, exacerbates tissue damage in myocardial infarction, and inhibits the repair of injured vascular endothelium. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Acute Phase Proteins
- Airway Inflammation and Remodeling
- C-Reactive Protein
- Glucose Homeostasis
- ICC / IHC Images: C-Reactive Protein/CRP
- Inflammatory Mediators
- Mouse Obesity Antibody Array
- Renal Markers
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