Quantikine Immunoassay Control Set 903 for Human CD163 (1 EA)
货号：
QC61 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC61 |
| 简介 | For use with catalog number DC1630 |
| 别名 | CD163 antigenscavenger receptor cysteine-rich type 1 protein M130; CD163 molecule; CD163; GHI/61; HbSR; Hemoglobin scavenger receptor; M130; M130macrophage-associated antigen; MM130; RM3/1 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 9332 (Human); 93671 (Mouse); 312701 (Rat) |
| 背景 | CD163, also known as M130 and p155, is a transmembrane scavenger receptor that is expressed on monocytes and macrophages and is inducible by immunosuppressant glucocorticoids and IL-10. A soluble form is shed from the cell surface by TACE or neutrophil elastase mediated cleavage in response to oxidative stress, Prostaglandin F2a stimulation, or the activation of Fc gamma receptors, TLR1, 2, 5, or 6. CD163 mediates monocyte binding to bacteria, leading to the release of inflammatory cytokines. It is essential for the circulatory clearance of hemoglobin-haptoglobin (Hb-Hp) complexes as well as free hemoglobin. It can also mediate monocyte-erythroblast adhesion and promote erythroblast expansion. CD163 binds and internalizes the cytokine TWEAK, and the ratio of soluble CD163 to TWEAK in the plasma is elevated during atherosclerosis. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Common Macrophage Markers
- Human CD Marker Products
- Langerhans and Dermal Dendritic Cells
- Leukocyte Receptors/Markers in Allergy and Asthma
- Lymphoma
- Macrophage Activation Markers
- Monocyte Markers
- Mouse Tissue-Resident Macrophage Markers
- Myeloid Lineage Markers
- Scavenger Receptors
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