概述货号 | QC56 |
简介 | For use with catalog number DCA125 |
别名 | CA125 ovarian cancer antigen; CA-125; CA125MUC-16; FLJ14303; MUC16; mucin 16, cell surface associated; mucin-16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125 |
全称 | Ovarian Cancer Antigen CA125 |
性能供应商 | R&D Systems |
Entrez Gene IDs | 94025 (Human) |
背景 | The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 | - Cancer Biomarkers
- Epithelial Cell Markers and Intracellular Molecules
- Special Glycoproteins
- Surface Ectodermal Cells
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