Quantikine Immunoassay Control Set 734 for Human BAFF/BLyS (1 EA)
货号：
QC46 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC46 |
| 简介 | For use with catalog numbers DBLYS0B, SBLYS0B, PDBLYS0B |
| 别名 | ApoL related ligand TALL-1; B lymphocyte stimulator; BAFFB-cell activating factor; B-cell-activating factor; BLyS; BLYSB-lymphocyte stimulator; CD257 antigen; CD257; Dendritic cell-derived TNF-like molecule; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; TNF- and APOL-related leukocyte expressed ligand 1; TNF and ApoL-related leukocyte expressed ligand 1; TNF homolog that activates apoptosis; TNFSF13B; TNFSF20; tumor necrosis factor (ligand) superfamily, member 13b; tumor necrosis factor (ligand) superfamily, member 20; tumor necrosis factor ligand superfamily member 13B; tumor necrosis factor superfamily, member 13b; tumor necrosis factor-like protein ZTNF4; ZTNF4 |
全称 | B cell Activating Factor |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 10673 (Human); 24099 (Mouse); 498666 (Rat) |
| 背景 | BAFF (B-cell activating factor), also known as BLyS, TALL-1, THANK, and TNFSF13B, is a TNF superfamily ligand that plays a critical role in the development and survival of B lineage cells. It can be expressed as a homotrimer or as a heteromer in association with the related protein APRIL. It is produced by many hematopoietic cell types, and a soluble form can be released by activated neutrophils. Both BAFF and APRIL signal through the receptors BCMA and TACI, and BAFF additionally signals through BAFF R. Mice that overexpress BAFF exhibit elevated B cell numbers, increased formation and size of germinal centers, and symptoms of autoimmunity. In addition, BAFF costimulates T cell activation, promotes a Th1 biased immune response, and promotes the expansion of Treg cells. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - BAFF and APRIL Involvement in B Cell Development
- Co-stimulatory and Co-inhibitory Molecules
- Human CD Marker Products
- ICC / IHC Images: BAFF/BLyS/TNFSF13B
- Regulation of Apoptosis by TNF Superfamily Members
- Regulation of B Cell Activation and Homeostasis by TNF Superfamily Members
- Regulation of T Cell Co-stimulation by TNF Superfamily Members
- TNF Homologue Implicated in Systemic Lupus Erythematosus (SLE)
- TNF Superfamily
- TNF Superfamily Ligands
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