概述货号 | QC34 |
简介 | For use with catalog number DAD120 |
别名 | a disintegrin and metalloproteinase domain 12 (meltrin alpha); ADAM 12; ADAM metallopeptidase domain 12; disintegrin and metalloproteinase domain-containing protein 12; EC 3.4.24; EC 3.4.24.58; MCMP; MCMPMltna; Meltrin alpha; meltrin-alpha; MLTNA; MLTNEC 3.4.24.- |
全称 | A Disintegrin and Metalloprotease-like Domain 12 |
性能供应商 | R&D Systems |
Entrez Gene IDs | 8038 (Human) |
背景 | Members of the ADAM or MDC (Metalloprotease, Disintegrin, Cysteine-rich) family contain pro, metalloprotease-like, disintegrin-like, cysteine-rich, transmembrane and cytoplasmic domains. They play a fundamental role in diverse processes such as asthma, development, angiogenesis and cancer through their activities in cell adhesion/fusion, membrane protein shedding, and signal transduction. Over 30 members have been identified and about half of them are active metalloproteases such as ADAM8, 9, 10, 12 and 17/TACE. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 | - Airway Inflammation and Remodeling
- Extracellular Matrix Remodeling and Cell Migration During EMT
- Metalloproteases and Regulators
- Mini-review: ADAMs
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