概述货号 | QC32 |
简介 | For use with catalog number DACE00 |
别名 | ACE1angiotensin converting enzyme, somatic isoform; angiotensin I converting enzyme (peptidyl-dipeptidase A) 1; carboxycathepsin; CD143 antigen; CD143; DCP; DCP1; DCP1angiotensin-converting enzyme; dipeptidyl carboxypeptidase 1; Dipeptidyl carboxypeptidase I; EC 3.2.1.-; EC 3.4.15.1; Kininase II; MGC26566; MVCD3; peptidase P; testicular ECA |
全称 | Angiotensin I Converting Enzyme |
性能供应商 | R&D Systems |
Entrez Gene IDs | 1636 (Human); 11421 (Mouse) |
背景 | ACE and ACE-2, two cell surface proteases, are important regulators of the renin-angiotensin system (RAS), which plays a key role in maintaining blood pressure homeostasis and fluid salt balance in mammals. Because of its location and specificity, ACE plays additional roles in immunity, reproduction and neuropeptide regulation. ACE exists in two isoforms. Somatic ACE comprises two highly similar protease domains whereas germinal ACE comprises a single protease domain. ACE-2 consists of a single protease domain and is an essential regulator of heart and lung function. It is also a cellular receptor for the Spike protein of SARS cornonavirus that causes severe acute respiratory syndrome. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 | - APP Cleavage and Amyloid-beta Degradation
- Cancer Biomarkers
- Endothelial Cell Markers
- Epithelial Cell Markers and Intracellular Molecules
- Hemangioblasts
- Human CD Marker Products
- ICC / IHC Images: ACE/CD143
- Interactive Pathway: A-beta Uptake & Degradation
- Metalloproteases and Regulators
- Neuronal Lineage Markers
- New Tools: Proteases & Inhibitors
- New Tools: Recombinant Proteases of the Renin-Angiotensin System (RAS)
- Renal Markers
- Renin-Angiotensin System
- Surface Ectodermal Cells
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