Quantikine Immunoassay Control Set 643 for Human IL-15 (1 EA)
货号：
QC26 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC26 |
| 简介 | For use with catalog numbers D1500, S1500, PD1500 |
| 别名 | IL-15MGC9721; interleukin 15; interleukin-15 |
全称 | Interleukin 15 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3600 (Human); 16168 (Mouse); 25670 (Rat); 493682 (Feline) |
| 背景 | IL-15 (Interleukin 15) is a cytokine that induces or enhances the differentiation, maintenance, or activation of multiple T cell subsets including NK, NKT, Th17, Treg, and CD8+ memory cells. It also induces dendritic cell differentiation and inflammatory activation, exhibits anti-tumor activity, and inhibits the deposition of lipid in adipocytes. Complexes of IL-15 with cell surface IL-15 R alpha interact with complexes of IL-2 R beta and the Common gamma Chain on adjacent cells. This transpresentation mechanism enables cells to respond to IL-15 even if they do not express IL-15 R alpha. Ligation of membrane-associated IL-15/IL-15 R alpha complexes also induces reverse signaling that promotes activation of the IL-15/IL-15 R alpha expressing cells. The activity of circulating IL-15 is limited by its association with soluble IL-15 R alpha. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - BIObrief: Common gamma-Chain Family Cytokines Play a Pivotal Role in Regulating Immune System Functions
- Common gamma Chain Receptor Family
- Common gamma-Chain Family Cytokines Play a Pivotal Role in Regulating Immune System Functions
- Group 1 ILCs
- ICC / IHC Images: IL-15
- Interactive Pathway: IL-15 Signaling and its Primary Biological Effects in Different Immune Cell Types
- Interactive Pathway: IL-15 Signaling Pathways
- Isolation, Culture, and Identification of Natural Killer Cells
- Macrophage Activation Markers
- Mini-review: Interleukin 15 (IL-15)
- Natural Killer T (NKT) Cells
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