Quantikine Immunoassay Control Set 883 Human Amyloid beta (1 EA)
货号：
QC216 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC216 |
| 简介 | For use with catalog numbers DAB140B and DAB142 |
| 别名 | Abeta; Amyloid beta; beta-Amyloid Peptide |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 351 (Human); 11820 (Mouse) |
| 背景 | Amyloid Precursor Protein (APP) is a type I transmembrane protein that is ubiquitously expressed on cell surfaces. It undergoes complex proteolytic processing and is cleaved by alpha-, beta-, and gamma-Secretases to generate soluble APP alpha, soluble APP beta, and Amyloid beta (A beta) fragments of several lengths. One of these fragments, A beta 42, generated by beta- and gamma-Secretase activities, has been implicated in Alzheimers disease. Aberrantly high levels of this peptide form and accumulate in the brains of Alzheimers disease patients to create the senile plaques characteristic of the disease. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Acute Phase Proteins
- APP Cleavage and Amyloid-beta Degradation
- Interactive Pathway: A-beta Plaque Formation & APP Metabolism
- Interactive Pathway: A-beta Uptake & Degradation
- Neurodegenerative Disease
- VPS10P-domain Family
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