概述货号 | QC215 |
简介 | For use with catalog number DHBEG0 |
别名 | diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor); Dtr; DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor); Dts; DTSF; Hegfl; heparin-binding EGF-like growth factor; heparin-binding epidermal growth factor; proheparin-binding EGF-like growth factor |
全称 | Heparin Binding EGF-like Growth Factor |
性能供应商 | R&D Systems |
Entrez Gene IDs | 1839 (Human); 15200 (Mouse) |
背景 | HB-EGF (Heparin-Binding EGF-like growth factor), also known as DTR, is produced by bronchial epithelium, visceral and vascular smooth muscle, CD4+ T cells, cardiac muscle, glomerular podocytes, keratinocytes, and IL-10-secreting regulatory macrophages. It activates both the EGF R/ErbB1 and ErbB4 receptors and has been linked to many cellular processes including proliferation, apoptosis, cell migration/invasion, differentiation, morphogenesis, and development. HB-EGF is also involved in several aspects of cancer development and progression. |
运输条件 | Blue Ice |
存放说明 | 4℃ |
参考文献 | - Cytokines and Receptors in Angiogenesis
- EGF Family
- EGF Ligands
- ICC / IHC Images: HB-EGF
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