概述| 货号 | QC209 |
| 简介 | For use with catalog number DTSE100 |
| 别名 | Endothelial plasminogen activator inhibitor; Nexin; PAI-1; PAI1PAI-1; PAISerpin E1; PLANH1; PLANH1plasminogen activator inhibitor 1; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogenactivator inhibitor type 1), member 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitortype 1), member 1 |
全称 | Plasminogen Activator Inhibitor |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 5054 (Human); 18787 (Mouse) |
| 背景 | The human serpin superfamily consists of at least 35 members that target not only serine proteases, but also selected cysteine proteases and non-protease proteins. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. As protease inhibitors, serpins have an array of functions including regulating blood clotting, the complement pathway, extracellular matrix remodeling, and cell motility. They are also involved in activities that extend beyond their ability to inhibit proteases. For instance, they may also regulate blood pressure, angiogenesis, or act as storage/transport proteins. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Adipocytokines
- Cancer Biomarkers
- Coagulation
- Complement Pathway
- DNA Damage and Repair
- ICC / IHC Images: Serpin E1/PAI-1
- Interactive Pathway: Blood Coagulation Signaling Pathways
- Mesenchymal Cells and EMT
- Plasmin/Plasminogen and Kallikrein/Kinin Systems
- Serine Proteases and Regulators
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