概述| 货号 | QC206 |
| 简介 | For use with catalog number DCD310 |
| 别名 | adhesion molecule; CD31 antigen; CD31; CD31/EndoCAM; endoCAM; FLJ34100; FLJ58394; GPIIA; PECA1; PECAM1; PECAM-1; PECAM-1, CD31/EndoCAM; platelet endothelial cell adhesion molecule; platelet/endothelial cell adhesion molecule |
全称 | Platelet Endothelial Cell Adhesion Molecule 1 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 5175 (Human); 18613 (Mouse); 29583 (Rat) |
| 背景 | CD31/PECAM-1 is a heavily glycosylated transmembrane homophilic adhesion protein that is highly expressed on endothelial cells and at a lower level on platelets, granulocytes, macrophages, dendritic cells, T and B cells, and NK cells. It is required for the transepithelial migration of leukocytes. CD31 signaling increases the activation threshold of T cells and inhibits dendritic cell development. The extracellular domain of CD31 is released during endothelial cell apoptosis. This fragment circulates in the serum of patients suffering from myocardial infarction, acute ischaemic stroke, and multiple sclerosis, conditions that involve tissue damage and endothelial cell apoptosis. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Cancer Biomarkers
- Endothelial Cell Differentiation Markers
- Endothelial Cell Markers
- Endothelial Cell Markers and Adhesion Molecules in Angiogenesis
- Endothelial Progenitor and Endothelial Cell Markers
- Endothelial Progenitor Cell Markers
- Hemangioblasts
- Human CD Marker Products
- ICC / IHC Images: CD31/PECAM-1
- Immunoglobulin Superfamily CAMs
- ITIM/ITAM Immunoreceptors and Related Molecules
- Mini-review: Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1/CD31)
- Myeloid-derived Suppressor Cells (MDSC)
- Platelets
- T Cell Migration/Adhesion
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