概述| 货号 | QC168 |
| 简介 | For use with catalog number DTGA00 |
| 别名 | protransforming growth factor alpha; TFGA; TGFA; transforming growth factor, alpha; transforming growth factor-alpha |
全称 | Transforming Growth Factor alpha |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 7039 (Human) |
| 背景 | TGF-alpha is a member of the EGF family of cytokines that are synthesized as transmembrane precursors with soluble forms released by proteolytic cleavage. Membrane-bound proTGF-alpha is biologically active and plays a role in mediation of cell-cell adhesion and in juxtacrine stimulation of adjacent cells. Expression of TGF-alpha is widespread in tumors and transformed cells. TGF-alpha is also expressed in normal tissues during embryogenesis and in adult tissues, including pituitary, brain, keratinocytes and macrophages. TGF-alpha binds and activates the EGF receptor. It induces fibroblast proliferation, epithelial development, keratinocyte migration, and angiogenesis. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Cytokines and Receptors in Angiogenesis
- EGF Family
- EGF Ligands
- HIF Transcription Factors
- ICC / IHC Images: TGF-alpha
- TGF-alpha: A New Job for an Old Friend
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