概述| 货号 | QC167 |
| 简介 | For use with catalog number DTFP10 |
| 别名 | convertin; EPI; EPITFPI1LACITFI; Extrinsic pathway inhibitor; LACI; Lipoprotein-associated coagulation inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); tissue factor pathway inhibitor |
全称 | Tissue Factor Pathway Inhibitor |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 7035 (Human); 21788 (Mouse) |
| 背景 | Human TFPI is a physiological inhibitor of the extrinsic pathway of coagulation and functions in anticoagulation and anti-inflammation. It is a secreted protein with an N-terminal acidic region, three Kunitz (K) domains separated by two linker regions, and a C-terminal basic region. The first K domain inhibits coagulation factor VIIa complexed to tissue factor (TF). The second K domain inhibits factor Xa. The third K domain binds to heparin. The C-terminal basic region may have several functions. Human TFPI-2 is structurally similar to TFPI and is downregulated in several cancers. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Coagulation
- Inflammatory Mediators
- Serine Proteases and Regulators
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