Quantikine Immunoassay Control Set 813 for Human HS PlGF (1 EA)
货号：
QC144 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC144 |
| 简介 | For use with catalog number HSPG00 |
| 别名 | D12S1900; PGF; PGFL; placenta growth factor; placental growth factor; placental growth factor, vascular endothelial growth factor-related protein; PlGF; PlGF-2; PLGFplacental growth factor-like; SHGC-10760 |
全称 | Placenta Growth Factor |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 5228 (Human); 18654 (Mouse) |
| 背景 | PlGF (placenta growth factor) is a homodimeric growth factor that competes with VEGF for binding to VEGF R1/Flt-1. It therefore increases the availability of VEGF to bind to VEGF R2/KDR/Flk-1 and trigger angiogenesis. It can form heterodimers with some forms of VEGF and decrease the angiogenic effect of VEGF on VEGF R2. Circulating PlGF levels increase during pregnancy, reaching a peak in mid-gestation; this increase is attenuated in preeclampsia. PlGF induces monocyte activation and migration as well as production of inflammatory cytokines and VEGF. These activities facilitate wound, bone fracture, and cardiac repair, but also contribute to inflammation in active sickle cell disease and atherosclerosis. PlGF can also inhibit TIMP3 expression in the spleen, leading to immune triggering of hypertension. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Epithelial Cell Markers and Intracellular Molecules
- HIF Transcription Factors
- ICC / IHC Images: PlGF
- New Tools: PlGF ELISA for Preeclampsia Research
- Preeclampsia
- Surface Ectodermal Cells
- Technical Notes: Serum Levels of Vascular Growth Factors During Pregnancy
- VEGF Family
- VEGF Family Ligands
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