概述| 货号 | QC103 |
| 简介 | For use with catalog number DHTR20 |
| 别名 | High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; Omi; OMIOmi stress-regulated endoprotease; PARK13EC 3.4.21.108; PRSS25; PRSS25serine, 25; Serine protease 25; serine protease HTRA2, mitochondrial; Serine proteinase OMI |
全称 | High Temperature Requirement Protein-2 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 27429 (Human); 64704 (Mouse) |
| 背景 | HTRA2/Omi is the mammalian homolog of the bacterial high temperature requirement protein (HTRA). HTRA2/Omi is a homotrimeric serine protease that localizes to the mitochondria and is processed to expose an N-terminal reaper-like motif similar to SMAC/Diablo. HTRA2/Omi is released from the mitochondria in response to apoptotic insult and can interact with the BIR2 or BIR3 domains of XIAP to relieve caspase-IAP inhibition. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Bcl-2 Proteins and Regulators
- ICC / IHC Images: HTRA2/Omi
- Inhibitors of Apoptosis (IAPs) and Regulators
- Mini-review: Apoptosis II: Beyond Cytochrome c; the Other Mitochondrial Proteins
- Mitochondrial Proteins
- New Tools: Proteases & Inhibitors
- Parkinsons Disease Related Molecules
- Serine Proteases and Regulators
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