Quantikine Immunoassay Control Set 582 Human CXCL1/GRO alpha ( )
货号：
QC101B 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC101B |
| 简介 | For use with catalog numbers DGR00B, SGR00B, PDGR00B |
| 别名 | CINC1; CINC-1; CXCL1; GRO alpha; KC; MGSA-alpha |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 2919 (Human); 14825 (Mouse); 81503 (Rat) |
| 应用文献 |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. Cell surface-anchored syndecan-1 ameliorates intestinal inflammation and neutrophil transmigration in ulcerative colitis
J Cell Mol Med, 2016;0(0):. 2016
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| 背景 | CXCL1/GRO alpha, also known as KC in mouse and CINC-1 in rat, is a member of the CXC family of chemokines. Human CXCL1/GRO alpha is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 57% and 59% amino acid sequence identity with the human protein, respectively. Genome-wide analysis suggests that the protein encoded by the mouse Cxcl3 gene is homologous to human CXCL1/GRO alpha protein. Human CXCL1/GRO alpha can be cleaved into three isoforms CXCL1/GRO alpha (aa 4-73), CXCL1/GRO alpha (aa 5-73), and CXCL1/GRO alpha (aa 6-73) which show higher activity than the full length protein. CXCL1/GRO alpha is secreted by mast cells and macrophages whereupon it acts as a chemoattractant for neutrophils. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Chemokines and Receptors in Allergy and Asthma
- Chemokines and Receptors in Angiogenesis
- CXC Chemokines and Receptors
- Inflammatory Mediators
- Macrophage Activation Markers
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