Quantikine Immunoassay Control Set 919 for Human Total IL-18 ( )
货号：
QC231 基本售价：
1774.7 元 规格：
1 Each
产品信息
概述| 货号 | QC231 |
| 简介 | For use with catalog number DL180 |
| 别名 | Iboctadekin; IFN-gamma-inducing factor; IGIF; IGIFIL-1 gamma; IL18; IL-18; IL-18MGC12320; IL-1F4; IL1F4iboctadekin; IL-1g; Interferon gamma-inducing factor; interleukin 18 (interferon-gamma-inducing factor); Interleukin-1 gamma; interleukin-18 |
全称 | Interleukin 18 |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3606 (Human); 16173 (Mouse); 29197 (Rat); 397057 (Porcine); 574151 (Primate) |
| 背景 | Interleukin 18 (IL-18), also known as interferon-gamma-inducing factor (IGIF) and IL-1γ, is a cytokine which shares biologic activities with IL-12 and structural similarities with the IL-1 family of proteins. IL-18 was originally cloned from liver cells and has since beenshown to be expressed by monocyte/macrophages, osteoblasts and keratinocytes. Caspase-1 (IL-1 beta-converting enzyme) has been implicated in the physiological processing of pro-IL-18 to IL-18. Similarly to IL-12, human IL-18 has been shown to enhance NK cell activity in PBMC cultures. Human IL-18 has also been found to induce the production IFN-γ and GM-CSF while inhibiting the production of IL-10 by PBMC. On enriched human T cells, human IL-18 can enhance Th1 cytokine production and stimulate cell proliferation via an IL-2-dependent pathway. In the mouse system, IL-18 has been shown to be a costimulatory factor for the activation of Th1, but not Th2, cells. IL-18 was found to selectively enhance the FasL-mediated cytotoxicity of Th1, but not Th0 or Th2, cells. IL-18 has also been shown to induce activated B cells to produce IFN-γ that inhibits IgE production. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 | - Cytokines and Receptors in Angiogenesis
- Group 1 ILCs
- IL-1 Family
- Isolation, Culture, and Identification of Natural Killer Cells
- Macrophage Activation Markers
- Molecules Secreted by VSMC
- Multiple Sclerosis and Myelin Related Molecules
- Neuroinflammation
- NOD-like Receptors and the Inflammasome
- T Cell Cytokine Signaling
- Th1 Cells
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