ProDots Recombinant Human VEGF 165 Protein (50 UG)【科瑞奥博】

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ProDots Recombinant Human VEGF 165 Protein (50 UG)

货号： PRD293-10 基本售价： 14871.7 元规格： 50 ug

产品信息

概述
货号	PRD293-10
简介	Supplied as ready-to-use 5 ug protein balls
别名	MVCD1; VAS; vascular endothelial growth factor A; Vascular permeability factor; Vasculotropin; VEGFA; VEGF-A; VEGFMGC70609; VPF; VPFvascular endothelial growth factor
全称	Vascular Endothelial Growth Factor
反应种属	Human
来源	Spodoptera frugiperda,Sf 21 (baculovirus)-derived Ala27 - Arg191
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)
内毒素水平	<0.01 EU per 1 μg of the protein by the LAL method.
生物活性	Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. Conn, G. et al. (1990) Proc. Natl. Acad. Sci. USA 87:1323. The ED₅₀ is typically 1.0-6.0 ng/mL.
溶解方法	Add ProDot directly to the medium or reconstitute at 100 μg/mL in sterile PBS. Alternatively, reconstitute at 500 μg/mL in sterile 4 mM HCl.
背景	VEGF (Vascular endothelial growth factor) is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is required for regulating the proliferation, migration, and survival of embryonic endothelial cells and during wound healing and the female reproductive cycle in adults. Pathologically, it is involved in tumor development and tumor vascular leakage. VEGF binds to VEGF R1/Flt-1, VEGF R2/Flk-1/KDR, and Neuropilin-1. Multiple forms of VEGF are generated by alternative splicing and proteolysis.
Accession #	NP_001165097
运输条件	Blue Ice
N-terminal Sequence Analysis	Ala27
预期分子量	19.2 (monomer) kDa
SDS-PAGE	20-22 kDa, reducing conditions 39-42 kDa, non-reducing conditions
存放说明	4℃
纯度	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
参考文献	Adipocytokines Adult Neurogenesis Airway Inflammation and Remodeling ALS Related Molecules BIObrief: Neuroprotective & Pathogenic Effects of VEGF Signaling Cancer Biomarkers Developmental Factors Implicated in Neurodegeneration HIF Transcription Factors HIF-1 & Vascular Development ICC / IHC Images: VEGF Inflammatory Mediators Macrophage Activation Markers Mini-review: Vascular Endothelial Growth Factor (VEGF) Myeloid-derived Suppressor Cells (MDSC) New and Improved TNF Superfamily Proteins 2015 Platelets Preeclampsia Proliferation Bioassay HUVECs Regulation of VE-Cadherin and VEGF R2 by VEGF Technical Notes: Serum Levels of Vascular Growth Factors During Pregnancy VEGF & Amyotrophic Lateral Sclerosis VEGF Family VEGF Family Ligands VEGF, Angiopoietin-2 and Tumor Vascularization

参考图片

1 μg/mL of ProDots^® Recombinant Human VEGF₁₆₅ was resolved by SDS-PAGE with silver staining, under reducing (R) and non-reducing (NR) conditions, showing major bands at 20-22 kDa and 39-42 kDa, respectively. Multiple bands in the gel are due to glycosylation.

ProDots^®VEGF₁₆₅ stimulates proliferation in HUVEC human umbilical endothelial cells. The ED₅₀ is typically 1.0-6.0 ng/mL.