ProDots Recombinant Human LIF Protein (250 UG)【科瑞奥博】

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ProDots Recombinant Human LIF Protein (250 UG)

货号： PRD7734-50 基本售价： 14871.7 元规格： 250 ug

产品信息

概述
货号	PRD7734-50
简介	Supplied as ready-to-use 5 ug protein balls
别名	CDF; D factor; DIA; differentiation inhibitory activity; differentiation stimulating factor; Differentiation-stimulating factor; Emfilermin; HILDAcholinergic differentiation factor; leukemia inhibitory factor (cholinergic differentiation factor); leukemia inhibitory factor; Melanoma-derived LPL inhibitor; MLPLI
全称	Leukemia Inhibitory Factor
反应种属	Human
来源	E. coli-derived Pro24 - Phe202
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3976 (Human); 16878 (Mouse); 403449 (Canine)
内毒素水平	<0.01 EU per 1 μg of the protein by the LAL method.
生物活性	Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. Kitamura, T. et al. (1989) J. Cell Physiol. 140:323.
背景	Based on its helical structure, LIF (Leukemia Inhibitory Factor) is considered a member of the Interleukin-6 family of cytokines. Functionally, it has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. Some cell types known to express LIF include activated T cells, monocytes, astrocytes, osteoblasts, keratinocytes, regenerating skeletal muscle, mast cells, and fibroblasts. The activities of LIF are mediated through a high-affinity heterodimeric receptor complex consisting of two membrane glycoproteins: an alpha subunit (LIF R alpha, also known as LIF R beta and CD118) that binds LIF with low affinity and the 130 kDa (gp130) subunit that does not bind LIF by itself, but is required for high-affinity binding of LIF by the complex.
Accession #	P15018
运输条件	Blue Ice
N-terminal Sequence Analysis	Pro24
预期分子量	19.6 kDa
SDS-PAGE	19 kDa, reducing conditions.
存放说明	4℃
参考文献	Cytokines and Receptors in Allergy and Asthma Diabetes Diabetes and Obesity Research Human Oncostatin M and Mouse LIF Support Mouse ES Cell Pluripotency & Germline Competency ICC / IHC Images: LIF IL-6 Family Megakaryocytes Mouse Obesity Antibody Array Obesity Reproduction

参考图片

1 μg/lane of ProDots^® Recombinant Human LIF was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized with silver staining, showing a single band at 19 kDa and 17 kDa, respectively.

ProDots^® Recombinant Human LIF demostrates cellproliferation activity in the TF-1 human erythroleukemic cell line.The ED₅₀ for this effect is typically 0.02-0.12 ng/mL.