ProDots Human G-CSF ( )【科瑞奥博】

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ProDots Human G-CSF ( )

货号： PRD214-01 基本售价： 3103.2 元规格： 5 ug

产品信息

概述
货号	PRD214-01
简介	Supplied as ready-to-use 5 ug protein balls
别名	C17orf33; chromosome 17 open reading frame 33; colony stimulating factor 3 (granulocyte); CSF3; CSF3OS; Filgrastim; GCSF; G-CSF; GCSFlenograstim; granulocyte colony-stimulating factor; Lenograstim; MGC45931; pluripoietin
全称	Granulocyte Colony Stimulating Factor
来源	E. coli-derived Thr31 - Pro204, with an -N-terminal Met
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	1440 (Human); 12985 (Mouse)
内毒素水平	<0.01 EU per 1 μg of the protein by the LAL method.
生物活性	Measured in a cell proliferation assay using NFS‑60 mouse myelogenous leukemia lymphoblast cells. Shirafuji, N.et al. (1989) Exp. Hematol. 17:116. The ED₅₀ for this effect is typically 10-60 pg/mL.
溶解方法	For a stock solution, reconstitute at 50 μg/mL in sterile PBS, or simply roll ProDot
背景	G-CSF (granulocyte-colony stimulating factor) is a secreted glycoprotein that regulates the proliferation, differentiation, and activation of neutrophilic granulocyte lineage cells. It also enhances M-CSF induced monocyte differentiation and the proliferation of Th2-inducing dendritic cells. G-CSF promotes the development of T cell immune tolerance as well as tissue recovery following myocardial infarction and cerebral ischemia. It signals through G-CSF R/CD114 on monocytes, neutrophils, megakaryocytes, platelets, myeloid progenitors, trophoblasts and placenta, endothelial cells, and various tumor cell types. Mutations in G-CSF R are associated with congenital neutropenia.
Accession #	NP_757373
运输条件	Blue Ice
N-terminal Sequence Analysis	Met
预期分子量	18.8 kDa
存放说明	4℃
纯度	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
参考文献	A novel role for the nervous system in HSPS mobilization ALS Related Molecules Cytokines and Receptors in Angiogenesis Gametes and Fertilization IL-6 Family Macrophage Activation Markers

参考图片

ProDots^® Recombinant Human G-CSF stimulated cell proliferation of the NFS-60 mouse myelogenous leukemia lymphoblast cell line. The ED₅₀ for this effect is typically
10-60 pg/mL.

1 μg/lane of ProDots^® Recombinant Human G-CSF was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized with silver staining, showing a single band at approximately 18 kDa.