ProDots Recombinant Human IFN-gamma Protein (50 UG)【科瑞奥博】

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ProDots Recombinant Human IFN-gamma Protein (50 UG)

货号： PRD285-10 基本售价： 2419.1 元规格： 50 ug

产品信息

概述
货号	PRD285-10
简介	Supplied as ready-to-use 5 ug protein balls
别名	IFG; IFI; IFNG; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma
全称	Interferon gamma
反应种属	Human
来源	E. coli-derived Gln24 - Gln166
产品组分

性能
供应商	R&D Systems
Entrez Gene IDs	3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline)
内毒素水平	<0.10 EU per 1 μg of the protein by the LAL method.
生物活性	Measured in anti-viral assays using HeLa human cervical epithelial carcinoma cells infected with encephalomyocarditis (EMC) virus. Meager, A. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 129. The ED₅₀ for this effect is typically 0.15-0.75 ng/mL.
溶解方法	Add ProDot directly to the medium or reconstitute in the vial at 200 μg/mL in sterile deionized water
背景	IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.
Accession #	CAA31639
运输条件	Blue Ice
N-terminal Sequence Analysis	Met
预期分子量	16.9 kDa
SDS-PAGE	17 kDa, reducing conditions
存放说明	4℃
纯度	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
参考文献	Conventional/Classical Dendritic Cells Cytokines and Receptors in Allergy and Asthma Cytokines and Receptors in Angiogenesis Cytokines and Receptors in Tfh Cell Differentiation and Function gamma delta T Cells Group 1 ILCs ICC / IHC Images: IFN-gamma IL-10/Interferon Family Infectious Diseases Inflammatory Mediators Interactive Pathway: Th1 Differentiation Isolation, Culture, and Identification of Natural Killer Cells Macrophage Activation Markers Multiple Sclerosis and Myelin Related Molecules Myeloid-derived Suppressor Cells (MDSC) Natural Killer T (NKT) Cells NCR+ILC3 NCR-ILC3 Neuroinflammation Regulatory T Cells (Tregs) T Cell Cytokine Signaling Th1 Cells

参考图片

1 μg/lane of ProDots^® Recombinant Human IFN-gamma was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized with silver staining, showing a single band at 17 kDa.

ProDots^® Recombinant Human IFN-gamma demonstrates anti-viral activity in HeLa human cervical epithelial carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED₅₀ for this effect is typically 0.15-0.75 ng/mL.