| 货号 | MS-343-R7 |
| 描述 | Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40 kDa. The basic keratins have molecular weights of 65-67, 64, 59, 58, 56 and 52 kDa. Members of acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with cell type, differentiation status and environment. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. Cellular Localization:Cytoplasmic Recommended for:
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| 克隆号 | AE1/AE3 |
| 同种亚型 | IgG1 + IgG1 |
| 反应种属 | Human, Monkey, Cow, Rabbit, Mouse, Rat and Chicken. Others not known. |
| 来源宿主 | Mouse |
| 供应商 | Labvision |
| 免疫原 | Human epidermal keratin |
| 存放说明 | 2-8摄氏度 |
| 参考文献 | 1. Woodcock-Mitchell J et al. Journal of Cell Biology, 1982 Nov, 95(2 Pt 1):580-8. 2. Tseng SC et al. Cell, 1982 Sep, 30(2):361-72. 3. Cooper D et al. Differentiation, 1984, 28::30-5. 4. Eichner R et al. J Cell Bio, 1984 98:1388-96. |
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