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货号： bs-21046R-Gold 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21046R-Gold
- 英文名称
- Anti-POU2F3/Gold
- 中文名称
- 胶体金标记的转录因子POU2F3抗体
- 别 名
- class 2; Epoc 1; Epoc1; HGNC19864; Oct 11; Oct-11; OCT11; Octamer binding transcription factor 11; Octamer-binding protein 11; Octamer-binding transcription factor 11; OTF-11; PLA 1; PLA1; PLA1 protein; PO2F3_HUMAN; POU class 2 homeobox 3; POU domain; POU domain transcription factor OCT11a; POU domain, class 2, transcription factor 3; POU transcription factor; POU2F3; Skn 1a; transcription factor 3; Transcription factor PLA-1; Transcription factor Skn-1; Transcription factor Skn1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul（10nm 15nm 35nm）
- 研究领域
- 肿瘤 细胞生物 转录调节因子 细胞分化 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 47kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human POU2F3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Function:
Transcription factor that binds to the octamer motif (5-ATTTGCAT-3). Regulated the expression of a number of genes such as SPRR2A or placental lactogen.
Subcellular Location:
Nucleus.
Tissue Specificity:
Specifically expressed in epidermis and cultured keratinocytes.
Similarity:
Belongs to the POU transcription factor family.
Class-2 subfamily.
Contains 1 homeobox DNA-binding domain.
Contains 1 POU-specific domain.
Database links:Entrez Gene: 25833Human
Entrez Gene: 18988Mouse
Entrez Gene: 116544Rat
Omim: 607394Human
SwissProt: Q9UKI9Human
SwissProt: P31362Mouse
SwissProt: P42571Rat
Unigene: 227115Human
Unigene: 325445Mouse
Unigene: 436650Mouse
Unigene: 81060Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.