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货号： bs-19958R-Gold 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19958R-Gold
- 英文名称
- Anti-PREB/Gold
- 中文名称
- 胶体金标记的催乳素调节元件结合蛋白PREB抗体
- 别 名
- Mammalian guanine nucleotide exchange factor mSec12; Preb; PREB_HUMAN; Prolactin regulatory binding element protein; Prolactin regulatory element binding; Prolactin regulatory element binding protein; Prolactin regulatory element-binding protein; SEC12.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul（10nm 15nm 35nm）
- 研究领域
- 细胞生物 发育生物学 生长因子和激素 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PREB
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein that specifically binds to a Pit1-binding element of the prolactin (PRL) promoter. This protein may act as a transcriptional regulator and is thought to be involved in some of the developmental abnormalities observed in patients with partial trisomy 2p. This gene overlaps the abhydrolase domain containing 1 (ABHD1) gene on the opposite strand. [provided by RefSeq, Jul 2008]
Function:
Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription (By similarity). Guanine nucleotide exchange factor that activates SARA2. Required for the formation of COPII transport vesicles from the ER.
Subcellular Location:
Nucleus. Endoplasmic reticulum membrane.
Tissue Specificity:
Ubiquitous.
Similarity:
Contains 3 WD repeats.
Database links:Entrez Gene: 10113Human
Entrez Gene: 50907Mouse
Entrez Gene: 58842Rat
Omim: 606395Human
SwissProt: Q9HCU5Human
SwissProt: Q9WUQ2Mouse
SwissProt: Q9WTV0Rat
Unigene: 279784Human
Unigene: 272414Mouse
Unigene: 41899Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.