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货号: bs-19856R-Gold 基本售价: 2980.0 元 规格: 100ul
产品信息
- 产品编号
- bs-19856R-Gold
- 英文名称
- Anti-phospho-RGS16 (Tyr168)/Gold
- 中文名称
- 胶体金标记的磷酸化G蛋白信号转导调节因子16抗体
- 别 名
- RGS16 (phospho Y168); p-RGS16 (phospho Y168);A28 RGS14; A28 RGS14P; A28-RGS14P; HGNC:9997; hRGS-r; OTTHUMP00000033147; Regulator of G protein signaling 16; Regulator of G protein signalling 16; Regulator of G-protein signaling 16; Retinal-specific RGS; Retinally abundant regulator of G protein signaling; Retinally abundant regulator of G-protein signaling; RGS 16; RGS R; RGS-R; Rgs14; RGS16; RGS16_HUMAN; RGSR.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul(10nm 15nm 35nm)
- 产品类型
- 磷酸化抗体
- 研究领域
- 细胞生物 信号转导 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthesised phosphopeptide derived from human RGS16 around the phosphorylation site of Tyr168
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene belongs to the regulator of G protein signaling family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha. May play a role in regulating the kinetics of signaling in the phototransduction cascade.
Tissue Specificity:
Abundantly expressed in retina with lower levels of expression in most other tissues.
Post-translational modifications:
Palmitoylated on Cys-2 and/or Cys-12.
Phosphorylation on Tyr-168 upon EGFR stimulation. Enhanced GTPase accelerating (GAP) activity on G(i)-alpha.
Similarity:
Contains 1 RGS domain.
Database links:Entrez Gene: 6004Human
Entrez Gene: 19734Mouse
Omim: 602514Human
SwissProt: O15492Human
SwissProt: P97428Mouse
Unigene: 413297Human
Unigene: 181709Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.