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货号： bs-17081R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-17081R
- 英文名称
- KATNAL2
- 中文名称
- KATNAL2蛋白抗体
- 别 名
- DKFZP667C165; Katanin p60 ATPase-containing subunit A-like 2; Katanin p60 subunit A like 2; Katanin p60 subunit A-like 2; KATL2_HUMAN; KATNAL 2; katnal2; MGC33211; p60 katanin like 2; p60 katanin-like 2.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 染色质和核信号 信号转导 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Rabbit,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 61kDa
- 细胞定位
- 细胞浆
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KATNAL2:401-500/538
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Microtubules are polymers of alpha and beta subunits that form the mitotic spindle and assist in the organization of membranous organelles during interphase. Katanin is a heterodimer complex that severs microtubules in an ATP-dependent manner. The severing of microtubules by the Katanin complex may promote reorganization of cellular microtubule arrays and release of microtubules from the centrosome following nucleation. The Katanin complex is composed of a 60 kDa subunit (Katanin p60 A1) and a 80 kDa accessory protein (Katanin p80 B1). Katanin p60 A1 is responsible for the severing and disassembly of microtubules, while Katanin p80 B1 targets the complex to the centrosome. Katanin p60 A1 and Katanin p80 B1 belong to the AAA ATPase family, which also includes the Katanin p60 A1-like proteins, Katanin p60 AL1 and Katanin p60 AL2.
Function:
Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
Subcellular Location:
Cytoplasm; cytoskeleton.
Similarity:
Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
A-like 2 sub-subfamily.
Contains 1 LisH domain.
SWISS:
Q8IYT4
Gene ID:
83473
Database links:Entrez Gene: 83473Human
Entrez Gene: 71206Mouse
Entrez Gene: 307253Rat
SwissProt: Q8IYT4Human
SwissProt: Q9D3R6Mouse
Unigene: 404137Human
Unigene: 35803Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Paraformaldehyde-fixed, paraffin embedded (mouse brain tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (KATNAL2) Polyclonal Antibody, Unconjugated (bs-17081R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.