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货号： bs-17082R-Gold 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17082R-Gold
- 英文名称
- Anti-KAZALD1/Gold
- 中文名称
- 胶体金标记的KAZALD1蛋白抗体
- 别 名
- Kazal-type serine protease inhibitor domain-containing protein 1; KAZALD1; KAZD1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul（10nm 15nm 35nm）
- 研究领域
- 细胞生物 发育生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 30kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KAZALD1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
BONO1, also known as KAZALD1 (kazal-type serine protease inhibitor domain-containing protein 1), IGFBP-rP10, FKSG28 or FKSG40, is a 304 amino acid secreted extracellular matrix protein that promotes matrix assembly. BONO1 is expressed in developing bones and odontoblasts in teeth, where it plays a role in osteoblast proliferation during bone formation and regeneration. BONO1 is also expressed at high levels in spleen, and is found at lower levels in lung, skin, urinary bladder, brain, tongue, kidney and large intestine. Existing as two alternatively spliced isoforms, BONO1 contains one Kazal-like domain, an IGFBP N-terminal domain and a single Ig-like C2-type (immunoglobulin-like) domain. The gene encoding BONO1 maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides. Cockayne syndrome, Cockayne syndrome and trisomy 10 are associated with defects in chromosome 10.
Function:
Involved in the proliferation of osteoblasts during bone formation and bone regeneration. Promotes matrix assembly.
Subcellular Location:
Secreted > extracellular space > extracellular matrix.
Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 IGFBP N-terminal domain.
Contains 1 Kazal-like domain.
Database links:Entrez Gene: 81621Human
SwissProt: Q96I82Human
Unigene: 534859Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.