产品中心
当前位置：首页>产品中心Anti-KIFC3/Gold
货号： bs-17060R-Gold 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17060R-Gold
- 英文名称
- Anti-KIFC3/Gold
- 中文名称
- 胶体金标记的驱动蛋白C3抗体
- 别 名
- DKFZp686D23201; FLJ34694; Kifc3; KIFC3_HUMAN; Kinesin family member C3; Kinesin-like protein KIFC3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul（10nm 15nm 35nm）
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 93kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KIFC3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
KIFC3 belongs to the large superfamily of kinesins, molecular motors that use the energy of ATP hydrolysis to translocate cargoes along microtubules. Members share extensive homology within a globular domain containing the microtubule- and ATP-binding sites and have a coiled-coil stalk domain that mediates oligomerization. Different kinesin family members participate in specific and diverse motile processes, such as cell division, organelle transport, and nuclear movement (Hoang et al., 1998 [PubMed 9782090]).[supplied by OMIM, Mar 2009]
Function:
Minus-end microtubule-dependent motor protein. Involved in apically targeted transport (By similarity). Required for zonula adherens maintenance.
Subcellular Location:
Cell junction > adherens junction. Cytoplasm > cytoskeleton > centrosome. Cytoplasmic vesicle membrane. Apical cell membrane. On membrane organelles immediately beneath the apical plasma membrane of renal tubular epithelial cells. Localized in the distal tubules and loops of Henle in the kidney, but not in the proximal tubules or the glomeruli, with stronger staining in the apical area of these epithelial cells (By similarity). Localizes along zonula adherens only at mature cell-cell contacts.
Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.
Database links:Entrez Gene: 3801Human
Entrez Gene: 16582Mouse
Entrez Gene: 307644Rat
Omim: 604535Human
SwissProt: Q9BVG8Human
SwissProt: O35231Mouse
Unigene: 23131Human
Unigene: 378951Mouse
Unigene: 14753Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.