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货号： bs-16831R-Gold 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16831R-Gold
- 英文名称
- Anti-KRT72/Gold
- 中文名称
- 胶体金标记的细胞角蛋白72抗体
- 别 名
- CK-72; Cytokeratin-72; K2C72_HUMAN; K6irs; K6IRS2; K72; KB35; Keratin 6 inner root sheath 2; keratin protein K6irs; Keratin type II cytoskeletal 72; Keratin-72; KRT6; KRT6IRS2; Krt72; Type II inner root sheath-specific keratin-K6irs2; Type-II keratin Kb35.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul（10nm 15nm 35nm）
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Rabbit,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 56kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KRT72
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2009]
Function:
Has a role in hair formation. Specific component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle.
Subunit:
Heterotetramer of two type I and two type II keratins.
Tissue Specificity:
Highly expressed in hair follicles from scalp and eyebrow. Also expressed in palmoplantar epidermis. Not expressed in face skin despite the presence of fine hairs histologically. In hair, it is specifically present in the inner root sheath (IRS) of the hair follicle. Present in the IRS cuticle, but not in Henle or Huxley layers of the IRS. In the IRS cuticle, its presence is delayed up to the height of the apex of the dermal papilla (at protein level).
Similarity:
Belongs to the intermediate filament family.
Database links:- Entrez Gene: 140807Human
- Omim: 608246Human
- SwissProt: Q14CN4Human
- Unigene: 662013Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.