产品中心
当前位置：首页>产品中心Anti-GPCR MRGE/GPCR GPR167/Gold
货号： bs-16269R-Gold 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16269R-Gold
- 英文名称
- Anti-GPCR MRGE/GPCR GPR167/Gold
- 中文名称
- 胶体金标记的G蛋白偶联受体167抗体
- 别 名
- G protein coupled receptor 167; G-protein coupled receptor 167; GPR167; Mas related G protein coupled MRGE; MAS related GPR member E; Mas-related G-protein coupled receptor member E; MRGE; MRGPRE; MRGRE_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul（10nm 15nm 35nm）
- 研究领域
- 信号转导 细胞凋亡 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 34kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GPCR MRGE/GPCR GPR167
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
MRGE is a 311 amino acid multi-pass membrane protein that acts as an orphan receptor and is though to influence nociceptor function. A member of the G-protein coupled receptor 1 family and MAS subfamily, MRGE is encoded by a gene that maps to human chromosome 11p15.4 and mouse chromosome 7 F5. Chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
Function:
Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain.
Subcellular Location:
Cell membrane.
Similarity:
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
Database links:Entrez Gene: 116534Human
Entrez Gene: 244238Mouse
Entrez Gene: 404660Rat
Omim: 607232Human
SwissProt: Q86SM8Human
SwissProt: Q91ZB7Mouse
SwissProt: Q7TN40Rat
Unigene: 706565Human
Unigene: 183561Mouse
Unigene: 189891Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.