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货号： bs-14491R-Gold 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14491R-Gold
- 英文名称
- Anti-EDC3/Gold
- 中文名称
- 胶体金标记的EDC3蛋白抗体
- 别 名
- EDC 3; edc3; EDC3_HUMAN; enhancer of mRNA decapping 3 homolog (S. cerevisiae); Enhancer of mRNA decapping 3 homolog; Enhancer of mRNA decapping 3, S. cerevisiae, homolog of; Enhancer of mRNA decapping protein 3; Enhancer of mRNA-decapping protein 3; FLJ21128; FLJ31777; hYjeF_N2; hYjeF_N2-15q23; LSM 16; LSM16; LSM16 homolog (EDC3 S. cerevisiae); LSM16 homolog (EDC3, S. cerevisiae); LSM16 homolog; YJDC; YjeF domain containing; YjeF domain containing protein 1; YjeF domain containing protein; YjeF domain-containing protein 1; YjeF N-terminal domain-containing protein 2; YjeF_N2; YJEFN2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul（10nm 15nm 35nm）
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 56kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human EDC3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).[supplied by OMIM, Mar 2008]
Edc3, enhancer of mRNA-decapping protein 3, is a 508 amino acid protein that maps to human gene EDC3. Edc3 is a member of the EDC3 family and contains one YjeF N-terminal domain. Edc3 is localized to the cytoplasm and is found primarily in the processing bodies (PBs) of the cell. Evidence indicates Edc3 also interacts with TTP (zinc finger protein 36), a candidate gene for obesity-related metabolic complications.
Function:
Binds single-stranded RNA. In the process of mRNA degradation, may play a role in mRNA decapping. May play a role in spermiogenesis and oogenesis.
Subcellular Location:
Cytoplasm; P-body. Processing bodies.
Tissue Specificity:
Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland.
Similarity:
Belongs to the EDC3 family.
Contains 1 DFDF domain.
Contains 1 YjeF N-terminal domain.
Database links:Entrez Gene: 80153Human
Entrez Gene: 453743Chimpanzee
Entrez Gene: 101128321Gorilla
Entrez Gene: 353190Mouse
Entrez Gene: 100171859Orangutan
Omim: 609842Human
SwissProt: Q96F86Human
SwissProt: Q8K2D3Mouse
SwissProt: Q5RDU9Orangutan
Unigene: 682454Human
Unigene: 96852Human
Unigene: 268104Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.