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货号： bs-14262R-Gold 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14262R-Gold
- 英文名称
- Anti-phospho-delta 1 Catenin (Tyr280)/Gold
- 中文名称
- 胶体金标记的磷酸化δ连环蛋白抗体
- 别 名
- delta 1 Catenin (phospho Y280); p-delta 1 Catenin (phospho Y280); Cadherin associated Src substrate; Cadherin-associated Src substrate; CAS; Catenin (cadherin associated protein) delta 1; Catenin delta 1; Catenin delta-1; CTND1_HUMAN; CTNND 1; CTNND; CTNND1; KIAA0384; p120; P120 CAS; p120 catenin; P120 CTN; p120(cas); p120(ctn); P120CAS; P120CTN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul（10nm 15nm 35nm）
- 产品类型
- 磷酸化抗体
- 研究领域
- 细胞生物 信号转导 干细胞 转录调节因子 细胞骨架
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 106kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthesised phosphopeptide derived from human delta 1 Catenin around the phosphorylation site of Tyr280
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010]
Function:
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Subcellular Location:
Cytoplasm. Nucleus. Cell membrane. Interaction with GLIS2 promotes nuclear translocation (By similarity). NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm.
Tissue Specificity:
Expressed in vascular endothelium.
Post-translational modifications:
Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ.
Similarity:
Belongs to the beta-catenin family.
Contains 10 ARM repeats.
Database links:Entrez Gene: 1500Human
Entrez Gene: 12388Mouse
Entrez Gene: 311163Rat
Omim: 601045Human
SwissProt: O60716Human
SwissProt: P30999Mouse
Unigene: 166011Human
Unigene: 35738Mouse
Unigene: 9435Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.