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货号： bs-14306R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-14306R
- 英文名称
- DCUN1D1
- 中文名称
- 鳞状细胞癌相关蛋白抗体
- 别 名
- DCN1 defective in cullin neddylation 1 domain containing 1; DCN1 like protein 1; DCNL1; DCNL1_HUMAN; DCUN1 domain containing protein 1; DCUN1L1; Defective in cullin neddylation protein 1 like protein 1; RP 42; RP42; RP42 homolog; SCCRO; SCRO; Squamous cell carcinoma related oncogene; Tes 3; Tes3.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 肿瘤细胞生物标志物 泛素
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Chicken, Cow, Horse,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 30kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DCUN1D1:1-100/259
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin. Forms part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. Defects in DCUN1D1 may be a cause of squamous cell carcinomas. Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.
SWISS:
Q96GG9
Gene ID:
54165
Database links:Entrez Gene: 54165Human
Entrez Gene: 424963Chicken
Entrez Gene: 539869Cow
Entrez Gene: 114893Mouse
Entrez Gene: 327232Zebrafish
Omim: 605905Human
SwissProt: Q5ZKU1Chicken
SwissProt: Q96GG9Human
SwissProt: Q9QZ73Mouse
Unigene: 104613Human
Unigene: 374810Mouse
Unigene: 379305Mouse
Unigene: 474495Mouse
Unigene: 113807Zebrafish
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample:
Epithelium (Mouse) Lysate at 40 ug
Primary: Anti-DCUN1D1 (bs-14306R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 30 kD
Observed band size: 30 kD