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货号： bs-13362R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-13362R
- 英文名称
- GJA10
- 中文名称
- 间隙连接蛋白10抗体
- 别 名
- Gap junction alpha 10; Connexin-62; Cx62; CXA10_HUMAN; Gap junction alpha 10; Gap junction alpha 10 protein; Gap junction alpha-10 protein; Gap junction protein alpha 10 59kDa; GJA10; MGC50985; RP11-63K6.6; Gap junction alpha 10; Connexin 58; Connexin 59; Connexin-62; CX58; CX59; Cx62; CXA10_HUMAN; Gap junction alpha 10; Gap junction alpha 10 protein; Gap junction alpha 9 protein; Gap junction alpha-10 protein; Gap junction protein alpha 10 59kDa; Gap junction protein alpha 9 59kDa; GJA10; MGC50985.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 心血管 细胞生物 细胞粘附分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Cow, Rabbit, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 62kDa
- 细胞定位
- 细胞膜
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GJA10:151-250/543 <Extracellular>
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008].
Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning.
Subunit:
A connexon is composed of a hexamer of connexins.
Subcellular Location:
Cell membrane. Cell junction; gap junction.
Tissue Specificity:
Expressed in skeletal muscle and heart.
Similarity:
Belongs to the connexin family. Alpha-type (group II) subfamily.
SWISS:
P57773
Gene ID:
84694
Database links:UniProtKB/Swiss-Prot: Q969M2.1
Entrez Gene: 84694Human
Omim: 611924Human
SwissProt: P57773Human
SwissProt: Q969M2Human
Unigene: 334499Human
Unigene: 632402Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Tissue/cell: Rat skeletal muscle; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-GJA10 Polyclonal Antibody, Unconjugated(bs-13362R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining