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货号： bs-12041R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-12041R
- 英文名称
- TAGLN3
- 中文名称
- 神经元蛋白22抗体
- 别 名
- Neuronal protein 22; Neuronal protein NP25; NP22; NP25; TAGL3_HUMAN; TAGLN3; Transgelin 3; Transgelin-3.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 神经生物学 干细胞
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 22kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TAGLN3/NP22:8-110/199
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
Transgelin is a homolog of transgelin and is also expressed in smooth muscle cells and by peritoneal B-1 cells. Unlike the other two transgelin proteins, transgelin-3 (also designated TAGLN2, NP22 (neuronal protein 22) or NP25) is predominantly expressed in brain. Transgelin-3 contains a putative Actin-binding domain, two EF-hand motifs, two potential phosphorylation sites and a calponin-homology (CH) domain. Transgelin-3 shares homology with transgelin and Calponin, two cytoskeleton-interacting proteins. Belonging to the calponin family, transgelin-3 colocalizes with Actin and Tubulin, suggesting a possible role for transgelin-3 in neuronal plasticity or as a signaling protein. Due to a varied expression pattern, transgelin-3 may play different roles in the developing and adult brain. Expression of transgelin-3 is upregulated in regions of the human alcoholic brain.
Tissue Specificity:
Widely expressed in the brain. Expression is increased in the superior frontal cortex of alcoholics, but not in the motor cortex or cerebellum.
Similarity:
Belongs to the calponin family.
Contains 1 calponin-like repeat.
Contains 1 CH (calponin-homology) domain.
SWISS:
Q9UI15
Gene ID:
29114
Database links:Entrez Gene: 29114Human
Entrez Gene: 56370Mouse
Entrez Gene: 63837Rat
Entrez Gene: 515562Cow
Omim: 607953Human
SwissProt: Q3ZBY2Cow
SwissProt: Q9UI15Human
SwissProt: Q9R1Q8Mouse
SwissProt: P37805Rat
Unigene: 169330Human
Unigene: 24183Mouse
Unigene: 10998Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Tissue/cell: Rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-TAGLN3 Polyclonal Antibody, Unconjugated(bs-12041R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining