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货号： bs-11381R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-11381R
- 英文名称
- A2LD1
- 中文名称
- A2LD1蛋白抗体
- 别 名
- A2ld1; GGACT_HUMAN; AIG2-like domain-containing protein 1; Gamma-glutamylaminecyclotransferase; GGACT.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse, Rabbit,
- 产品应用
- ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 17kDa
- 细胞定位
- 细胞外基质 分泌型蛋白
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human A2LD1:1-50/153
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
A2LD1 is a 153 amino acid protein belonging to the gamma-glutamylcyclotransferase family. A2LD1 contains two exons, with only the second exon coding, and spans 2.2 kb. Consisting of a monomer subunit, A2LD1 participates in acyltransferase and gamma-glutamylcyclotransferase activities. A2LD1 assists with the breakdown of proteins cross-linked by transglutaminases. A2LD1 also catalyzes the formation of 5-oxoproline from L-gamma-glutamyl-L-epsilon-lysine, but is inactive with L-gamma-glutamyl-alpha-amino acid substrates, such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine. A2LD1 is encoded by a gene that maps to human chromosome 13q32.3.
Function:
Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. Catalyzes the formation of 5-oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.
Subunit:
Monomer.
Similarity:
Belongs to the gamma-glutamylcyclotransferase family.
SWISS:
Q9BVM4
Gene ID:
87769
Database links:Entrez Gene: 87769Human
Omim: 613378Human
SwissProt: Q9BVM4Human
Unigene: 350868Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-A2LD1 Polyclonal Antibody, Unconjugated(bs-11381R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining