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货号： bs-9542R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-9542R
- 英文名称
- C7orf27
- 中文名称
- 7号染色体开放阅读框27抗体
- 别 名
- BAAT 1; BAAT1; BRAT-1; brat1; BRAT1_HUMAN; BRCA1-associated ATM activator 1; BRCA1-associated protein required for ATM activation protein 1; BRCA1-associated protein required for ATM activation-1; C7orf27; chromosome 7 open reading frame 27; HEAT repeat containing protein C7orf27.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 88kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human BAAT1/C7orf27:21-120/821
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- Function:
Required for activation of ATM following ionizing radiation. May act by regulating dephosphorylation of ATM.
Subunit:
Interacts with BRCA1 and ATM.
Subcellular Location:
Nucleus. Present at double strand breaks (DSBs) following ionizing radiation treatment.
Tissue Specificity:
Ubiquitously expressed.
DISEASE:
Defects in BRAT1 are the cause of rigidity and multifocal seizure syndrome, lethal neonatal (RMFSL) [MIM:614498]. A lethal, neonatal, neurologic disorder characterized by episodic jerking that is apparent in utero, lack of psychomotor development, axial and limb rigidity, frequent multifocal seizures, and dysautonomia. At birth, affected individuals have small heads, overlapping cranial sutures, small or absent fontanels, and depressed frontal bones. Infants show poorly responsive focal jerks of the tongue, face and arms in a nearly continuous sequence throughout life.
Similarity:
Contains 2 HEAT repeats.
SWISS:
Q6PJG6
Gene ID:
221927
Database links:Entrez Gene: 221927 Human
Entrez Gene: 231841 Mouse
SwissProt: Q6PJG6 Human
SwissProt: Q8C3R1 Mouse
SwissProt: D3ZUM1 Rat
Unigene: 520623 Human
Unigene: 271932 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample: 293T Cell (Human) Lysate at 30 ug
Primary: Anti-C7orf27 (bs-9542R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 88kD
Observed band size: 88kD