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货号： bs-8462R-Gold 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8462R-Gold
- 英文名称
- Anti-APLP2/Gold
- 中文名称
- 胶体金标记的淀粉样蛋白β前体样蛋白2抗体
- 别 名
- amyloid beta (A4) precursor like protein 2; Amyloid like protein 2; amyloid precursor protein homolog HSD2; Amyloid protein homolog; Amyloid-like protein 2; APLP-2; Aplp2; APLP2_HUMAN; APPH; APPL2; CDEBP; CDEI box binding protein; CDEI box-binding protein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul（10nm 15nm 35nm）
- 研究领域
- 细胞生物 免疫学 神经生物学 Alzheimers
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Horse,
- 产品应用
- IEM=1:20-200 IGS=1:20-200 GICA=1:20-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 80kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human APLP2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5-GTCACATG-3(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Function:
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5-GTCACATG-3(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Subunit:
Interacts with CPEB1.
Subcellular Location:
Cell membrane. Nucleus.
Tissue Specificity:
Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
Post-translational modifications:
The BPTI/Kunitz inhibitor domain is O-glycosylated.
Similarity:
Belongs to the APP family.
Contains 1 BPTI/Kunitz inhibitor domain.
Database links:Entrez Gene: 334Human
Entrez Gene: 11804Mouse
Entrez Gene: 64312Rat
Omim: 104776Human
SwissProt: Q06481Human
SwissProt: Q06335Mouse
SwissProt: P15943Rat
Unigene: 370247Human
Unigene: 19133Mouse
Unigene: 129285Rat
Unigene: 1423Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.