| 货号 | BAF1238 |
| 描述 | For ELISA the Antibody Pairs information：Capture antibody：AF1238；Detection antibody：BAF1238; and protein: 1238-PI-010 |
| 别名 | ARMD11; bA218C14.4 (cystatin C); CST3; cystatin 3; cystatin C (amyloid angiopathy and cerebral hemorrhage); cystatin C; cystatin-3; cystatin-C; Gamma-trace; MGC117328; Neuroendocrine basic polypeptide; Post-gamma-globulin |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) ELISA Capture (Matched Antibody Pair)(0.2-0.8 µg/mL ) ELISA Detection (Matched Antibody Pair)(0.1-0.4 µg/mL ) ELISA Standard ( ) |
| 目标/特异性 | Detects mouse Cystatin C in ELISAs and Western blots. In sandwich ELISAs, approximately 30% cross-reactivity with recombinant rat Cystatin C is observed, less than 0.2% cross-reactivity with recombinant human (rh) Cystatin C is observed and less than 0.4% cross‑reactivity with recombinant mouse (rm) Cathepsin B, rmActive Cathepsin C (2336-CY), rmCathepsin C (1034-CY), rmCathepsin D, rmCathepsin E, rmCathepsin H, rmCathepsin L, rmCathepsin X/Z/P, rmCystatin B, rmCystatin E/M and rmCystatin F is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL ELISA Capture (Matched Antibody Pair): 0.2-0.8 µg/mL ELISA Detection (Matched Antibody Pair): 0.1-0.4 µg/mL ELISA Standard : |
| 来源 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 1471 (Human); 13010 (Mouse); 25307 (Rat) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse Cystatin C Ala21-Ala140 Accession # P21460 |
| 生物活性 | Mouse |
| 标记 | Biotin |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Cystatin C is a member of family 2 of the cystatin superfamily (1). It is involved in processes such as tumor invasion and metastasis, inflammation and some neurological diseases. It inhibits many cysteine proteases such as papain and cathepsins B, H, K, L and S (2, 3). All mouse tissues analyzed expressed Cystatin C, with relative levels similar to those of rat and human tissues. For all three species, brain and liver had the highest and lowest levels of Cystatin C, respectively, whereas kidney, spleen and muscle had the levels in between (4). The high degree of similarity in distribution and functional properties for mouse, rat and human Cystatin C indicates that a murine model should be relevant for studies of the human disease, hereditary Cystatin C amyloid angiopathy (4). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 参考文献 |
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