Mouse IFN-alpha Polyclonal Ab (20000 UN)
货号：
32100-1 基本售价：
5314.1 元 规格：
-
产品信息
概述| 货号 | 32100-1 |
| 描述 | For ELISA the Antibody Pairs information：Capture antibody：22100-1；Detection antibody：32100-1; and protein: 12100-1 |
| 别名 | IFNalpha; IFN-alpha |
全称 | Interferon alpha | | 应用 | Neutralization |
| 目标/特异性 | Mouse IFN-alpha
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| 使用方法 | Neutralization: One Neutralization Unit (NU) is the amount of antiserum required to neutralize one unit of mouse interferon alpha (Mu-IFN-alpha ) to a 50% endpoint. Interferon was titrated with the use of the cytopathic effect inhibition assay using L929 cells as described [Rubinstein, S., Familletti, P.C., and Pestka, S. (1981) "Convenient Assay for Interferons," J. Virol. 37, 755-758] with the exception that EMCV was used as the challenge virus. In this antiviral assay for interferon, about 5 unit/ml of interferon is the quantity necessary to produce a cytopathic effect of 50%. The units are determined with respect to the international reference standard for Mu-IFN-alpha provided by the National Institutes of Health [Ga02-901-511). This material is prepared specifically for effective neutralization of Mu-IFN-alpha.
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| 来源 | Polyclonal Rabbit Serum |
| 产品组分 | |
性能| 供应商 | R&D Systems |
| Entrez Gene IDs | 3440 (Human) |
| 应用文献 |
| R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions. A role for Stat1 in the regulation of lipopolysaccharide-induced interleukin-1beta expression.
Authors: Joshi VD, Kalvakolanu DV, Chen W, Zhang L, Kang TJ, Thomas KE, Vogel SN, Cross AS
J. Interferon Cytokine Res., 2006;26(10):739-47.
Species: Mouse
Sample Type: Serum
Application: ELISA Development |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | E. coli-derived recombinant mouse IFN-alpha A |
| 生物活性 | Rat |
| 标记 | Unconjugated |
| 背景 | Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells. |
| 运输条件 | Dry Ice |
| 存放说明 | -20℃ |
| 参考文献 | - B Cell Chemotaxis, Migration, and Adhesion
- Cytokines and Receptors in Angiogenesis
- IL-10/Interferon Family
- Infectious Diseases
- Plasmacytoid Dendritic Cells
- Th9 Cells
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