| 货号 | AF1989-SP |
| 别名 | CAP-2; CAPH2; channel-activating protease 2; EC 3.4.21; EC 3.4.21.-; EC 3.4.21.4; EC 3.4.21.43; marapsin; MPN; MPNMarapsin; Pancreasin; protease, serine 27; PRSS27; serine protease 27 |
| 反应种属 | Mouse |
| 应用 | Western Blot(0.1 µg/mL) Immunoprecipitation(25 µg/mL) |
| 目标/特异性 | Detects mouse Marapsin/Pancreasin in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human Marapsin is observed. |
| 使用方法 | Western Blot: 0.1 µg/mL Immunoprecipitation: 25 µg/mL Neutralization: Measured by its ability to neutralize Recombinant Mouse Marapsin/Pancreasin (0.5 µg/mL, Catalog # 1989-SE) cleavage of the colorimetric peptide substrate Z-GR-SBzl (100 µM) in the presence of DTNB (100 µM). The Neutralization Dose (ND50) is typically 5 µg/mL. |
| 来源 | Polyclonal Goat IgG |
| 产品组分 |
| 供应商 | R&D Systems |
| Entrez Gene IDs | 83886 (Human); 213171 (Mouse) |
| 纯化方式 | Antigen Affinity-purified |
| 免疫原 | Mouse myeloma cell line NS0-derived recombinant mouse Marapsin/Pancreasin Ala23-Thr290 Accession # Q8BJR6 |
| 生物活性 | Mouse |
| 标记 | Unconjugated |
| 溶解方法 | Reconstitute at 0.2 mg/mL in sterile PBS. |
| 背景 | Marapsin, pancreasin, and channel-activating protease 2 (CAP-2) are different names for the same serine protease that is expressed strongly in the pancreas. Synthesized as a single-chain proenzyme, marapsin is activated to form a disulfide bond-linked dimer between the pro peptide and the serine protease domain. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 参考文献 |
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